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What is Nolvadex? Nolvadex is used to treat certain types of breast cancer in men and women. Nolvadex is also given to women to help prevent breast cancer when they may have a high risk for the disease, such as a family history. Nolvadex works by blocking the actions of estrogen, which is needed for some types of breast cancer to grow and spread. Nolvadex may also be used for conditions that are not described in this medication guide. Key Facts About Nolvadex Nolvadex works by blocking the actions of estrogen. Certain types of breast tumors need estrogen to grow. If you have been prescribed Nolvadex to reduce your risk of breast cancer, your first dose may need to be taken while you are having a menstrual period.

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