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Although Furosemide in 1962 came on the market, it is still the most powerful diuretic that is available. Here you can read everything you need to Furosemide, side effects and use. How it works? In the kidney, the blood is filtered. Here waste products, pollutants and some drugs are extracted and ultimately excreted in the urine. The smallest functional unit of the kidney is in the nephron, which consists of the glomeruli and renal tubules one. Many of these nephrons are connected in parallel and filter small molecules from the blood blood proteins and blood cells remain in the blood.

The resulting primary urine is still unfocused and is concentrated in the renal tubules by the resumption of the water contained. In this case, other substances which are essential for the body, but have been filtered out for example, glucose, sodium, potassium and chloride ions , again absorbed into the blood. It inhibits here the resumption of sodium, potassium and chloride ions — they leave the body with the urine. Along with these charged particles and large quantities of water are excreted, which is actually intended Furosemide effect.

At high doses of Furosemide urine amounts of up to 50 liters a day. Increased excretion of water lowers the blood pressure. The effect occurs after about half an hour. Only a small portion of the drug is metabolized in the liver about ten percent , the rest is excreted unchanged — about one-third with the chair, the remaining amount in the urine. After about one hour, the active ingredient is excreted in half. Uses The active ingredient Furosemide is used for:

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