If you have recently been prescribed a medicine to prevent gout attacks such as allopurinol, febuxostat, or sulfinpyrazone and you have been given colchicine to prevent a flare-up attack of gout, the usual dose for this is one tablet twice each day. Take colchicine tablets with a drink of water. If you forget to take a dose, take it as soon as you remember unless it is nearly time for your next dose, in which case leave out the missed dose. Do not take two doses together to make up for a forgotten dose. Getting the most from your treatment Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. Do not drink grapefruit juice while you are on colchicine.
This is because grapefruit juice increases the risk that you will experience side-effects from the colchicine. Colchicine tablets are taken in short courses of treatment to relieve the pain of a gout attack. There are a number of lifestyle changes that you can make to help reduce the risk of having a gout attack. These include losing weight if you are overweight , eating a healthy diet and not drinking much alcohol or sugar-sweetened soft drinks. Your doctor will advise you about the changes which could benefit you. Never take more than the prescribed dose. Taking too much colchicine can cause serious problems. If you suspect that someone has taken an overdose of colchicine or has swallowed some by accident, you must contact a doctor straightaway.
Alternatively, go to the accident and emergency department of a local hospital. Do not delay. Take the container with you, even if it is empty. This is so the doctor knows what has been taken. Can colchicine cause problems? While colchicine is reserved for use in adults with acute gout flares, it can be used prophylactically in adolescents 16 and over. Its only approved use in children is for the treatment of familial Mediterranean fever FMF. Side Effects Adverse reactions can occur with colchicine use and it's important for you to be aware of that potential. Bone marrow depression, with aplastic anemia, with agranulocytosis, or with thrombocytopenia may occur in people receiving long-term therapy.
Other possible adverse reactions include: Peripheral neuritis. Tell your doctor if you are pregnant or plan to become pregnant. Colchicine can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby. How should I take colchicine? Do not purchase colchicine on the Internet or from vendors outside of the United States. Using this medication improperly or without the advice of a doctor can result in serious side effects or death. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Colchicine can be taken with or without food.
To treat a gout attack, for best results take colchicine at the first sign of the attack. The longer you wait to start taking the medication, the less effective it may be. You may need to take a second lower dose of colchicine 1 hour after the first dose if you still have gout pain. Follow your doctor's instructions. Your dose will depend on the reason you are taking this medicine. Colchicine doses for gout and Mediterranean fever are different. Do not stop using colchicine unless your doctor tells you to, even if you feel fine.
5/17/ · Colchicine is taken to ease the pain of a gout attack. Take one tablet times a day until the pain eases, unless your doctor tells you otherwise. Do not take more than 12 tablets during any one attack. Common side-effects are feeling sick and diarrhoea. If this happens, stop taking colchicine and let your symptoms settle. 3/25/ · Colchicine can be taken with or without food. To treat a gout attack, for best results take colchicine at the first sign of the attack. The longer you wait to start taking the medication, the less effective it may be. You may need to take a second lower dose of colchicine 1 hour after the first dose if you still have gout pain. Colchicine. We explain everything you need to know about taking colchicine tablets for gout. 02/11/ What is colchicine used for? Relieving the pain of acute attacks of gout. 3/25/ · Colchicine is a prescription medication available under the brand name Colcrys or in generic form. Colchicine is a preferred treatment for gouty arthritis and is derived from the dried seeds of Colchicum autumnale (also known as the autumn crocus or meadow saffron).
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All patients developed GI symptoms. One developed life-threatening symptoms requiring hospitalization. Two cases of severe toxicity from interaction with clarithromycin and one case with tacrolimus were reported to DPIC. Concomitant use of clarithromycin and colchicine has resulted in death. Ensure patients understand how to take colchicine and what their maximum daily dose is. Ensure patients understand that colchicine is not a painkiller, i. In 29 per cent of therapeutic errors reported to DPIC, patients took their doses incorrectly: All developed GI symptoms; one required hospitalization.
Deaths have been reported in the literature. Instruct patients to stop colchicine and call their prescriber or pharmacist if they develop GI side effects or symptoms of myoneuropathy muscle pain, fatigue, weakness, numbness. Some patients continue taking colchicine despite side effects, which can result in worsening of toxicity. Advise patients who take multiple medications to be careful when taking their medications and to keep all medications for family members in separate locations. Store at room temperature. Store in a dry place. Do not store in a bathroom. Protect from light.
Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets. Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area. Consumer information use If your symptoms or health problems do not get better or if they become worse, call your doctor. Do not share your drugs with others and do not take anyone else's drugs.
Keep a list of all your drugs prescription, natural products, vitamins , OTC with you. Give this list to your doctor. Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins. This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Colchicine also has a suppressive effect that helps to decrease acute gout attacks , thereby relieving pain and discomfort associated with gout. Dosages Colchicine is available in two oral strengths: For the treatment of acute gout, the recommended dosage for adults is 1.
You can continue with an additional 0. White blood cells migrate to the areas of the body where uric acid has been deposited. They attempt to engulf the crystals, and, as a result, lactic acid and pro-inflammatory enzymes are released. These substances cause the characteristic pain and swelling of gout. Colchicine stops white blood cells moving into the inflamed areas and this reduces pain and inflammation in the joint. Before taking colchicine Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking colchicine it is important that your doctor knows: If you are pregnant, trying for a baby or breastfeeding.
If you have any problems with the way your heart or liver works, or any problems with the way your kidneys work. If you have any problems with your digestive system. If you have a blood disorder. If you are taking or using any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines. If you have ever had an allergic reaction to a medicine. How to take colchicine Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack.
It will give you more information about colchicine and will provide you with a full list of the side-effects which you may experience from taking it. You must take colchicine exactly as your doctor tells you to.